Game&watch even did make it to the movies! In the film Die Story, an actor plays with a Mickey Mouse MC-25. Or at least he tries to play...http://www.youtube.com/watch?v=jdXwneNLRIQ
In another movie named K9 a G&W is supposed to appear as well. As soon as I have this movie, I'll tell you more.
Do you know other films where Game&Watch plays a role?